Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway 2.93MB

Authors: J. C. Lee, M. Espéli, C. A. Anderson, M. A. Linterman, J. M. Pocock, N. J. Williams, R. Roberts, S. Viatte, B. Fu, N .Peshu, T. T. Hien, N. H. Phu, E. Wesley, C. Edwards, T. Ahmad, J. C. Mansfield, R. Gearry, S. Dunstan, T. N. Williams, A. Barton, G. C. Vinuesa, UK IBD Genetics Consortium; M. Parkes, P.A. Lyons and K. G. C. Smith

Journal: Cell

Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis 1.42MB

Authors: J. C. Lee, P. A. Lyons, E. F. McKinney, J. M. Sowerby, E. J. Carr, F. Bredin, H. M. Rickman, H. Ratlamwala, A. Hatton, T. F. Rayner, M. Parkes, K. G. C. Smith

Journal: The Journal of Clinical Investigation

A CD8 + T cell transcription signature predicts prognosis in autoimmune disease 0.00 KB

Authors: E. F. McKinney, P. A. Lyons, E. J. Carr, J. L. Hollis, D. R. W. Jayne, L. C. Willcocks, M. Koukoulaki, A. Brazma, V. Jovanovic, D. M. Kemeny, A. J. Pollard, P. A. MacAry, A. N. Chaudhry and K. G C. Smith

Journal: Nature Medicine

Novel expression signatures identified by transcriptional analysis of separated leucocyte subsets in systemic lupus erythematosus and vasculitis 0.3MB

Authors: P. A. Lyons, E. F McKinney, T. F. Rayner, A. Hatton, H. B. Woffendin, M. Koukoulaki, T. C. Freeman, D. R. W. Jayne, A. N. Chaudhry and K. G. C. Smith

Journal: Annals of the Rheumatic Diseases

Microarray analysis of human leucocyte subsets: the advantages of positive selection and rapid purification 1.41 MB

Authors: P. A. Lyons, M. Koukoulaki, A. Hatton, K. Doggett, H. B. Woffendin, A. N. Chaudhry, and K. G. C. Smith

Journal: BMC genomics

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