Resources
A blood-based prognostic biomarker in IBD 1MB
Authors: D. Biasci, J. C. Lee, N. M. Noor, D. R. Pombal, M. Hou, N. Lewis, T. Ahmad, A. Hart, M. Parkes, E. F. McKinney, P. A. Lyons and K. G. C. Smith
Journal: Gut
PRedicting Outcomes For Crohn’s dIsease using a moLecular biomarkEr (PROFILE): protocol for a multicentre, randomised, biomarker-stratified trial 0.54MB
Authors: M. Parkes, N. M. Noor, F. Dowling, H. Leung, S. Bond, L. Whitehead, S. Upponi, P. Kinnon, A. P. Sandham, P. A. Lyons, E. F. McKinney, K. G. C. Smith and J. C. Lee
Journal: BMJ Open
From Big Data to Precision Medicine 2MB
Authors: T. Hulsen, S. S. Jamuar, A. R. Moody, J. H. Karnes, O. Varga, S. Hedensted, R. Spreafico, D. A. Hafler and E. F. McKinney
Journal: Frontiers in Medicine
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease 0.00 KB
Authors: J. C. Lee, D. Biasci, R. Roberts, R. B. Gearry, J. C. Mansfield, T. Ahmad, N. J. Prescott, J. Satsangi, D. C. Wilson, L. Jostins, C. A. Anderson, UK IBD Genetics Consortium; J. A. Traherne, P. A. Lyons, M. Parkes and K. G. C. Smith
Journal: Nature Genetics
T-cell exhaustion: understanding the interface of chronic viral and autoinflammatory diseases 0.00 KB
Authors: E. F. McKinney and K. G. C. Smith
Journal: Immunology & Cell Biology
T cell exhaustion and immune-mediated disease - the potential for therapeutic exhaustion 0.00 KB
Authors: E. F. McKinney and K. G. C. Smith
Journal: Current Opinion in Immunology
T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection 0.00 KB
Authors: E. F. McKinney, J. C. Lee, D. R. W. Jayne, P. A. Lyons and K. G. C. Smith
Journal: Nature
T-cell exhaustion limits immune reactivity and is associated with good prognosis in autoimmune disease 0.42MB
Authors: E. F. Carney
Journal: Nature Reviews Rheumatology
Signatures of CD4 T-cell help and CD8 exhaustion predict clinical outcome in autoimmunity, infection, and vaccination 41.5KB
Authors: E. F. McKinney, J. C. Lee, P. A. Lyons, T. F. Rayner, E. J. Carr, A. Hatton, D. R. W. Jayne, L. C. Willcocks, A. N. Chaudhry and K. G. C Smith
Journal: The Lancet
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