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The IBD biomarker was originally discovered using gene expression analysis of CD8+ T cells (Lee 2011, McKinney 2015) and subsequently translated into a 17 gene (15 informative, 2 control genes) whole blood qPCR test, validated on an independent cohort of 123 IBD patients (66 CD, 57 UC) (Biasci 2019).
PredictSURE IBD test clinical validation
Results based on validation in a cohort of patients independent from the discovery cohort
1. PredictSURE IBD Clinical Validation (PredictSURE IBD IFU, see Biasci et al. 2019 for longer term follow up)
*in the first 12 months of follow up